Olmesartan-Associated Enteropathy: A Review of Clinical and Histologic Findings.

奥美沙坦相关的肠道病变：一项临床和组织学综述

Choi EY,McKenna BJ

阅读：412 Archives of Pathology & Laboratory Medicine； Volume 139, Issue 10 (October 2015):1242-7

Abstract

Olmesartan is an antihypertensive medication belonging to the angiotensin II receptor blocker class of drugs that has recently been associated with severe enteropathy. Olmesartan-associated enteropathy is uncommon and may be difficult to recognize because of its clinical and histologic similarities to other clinical entities, including celiac sprue and autoimmune enteropathy. The purpose of this article is to review the clinical and histologic findings of olmesartan-associated enteropathy that have been reported in the literature and to discuss clinical entities to consider in the differential diagnosis of olmesartan-associated enteropathy.

摘要

奥美沙坦是一种属于血管紧张素Ⅱ受体阻断剂类的降压药，最近发现与严重肠道病变有关。奥美沙坦相关的肠道病变并不常见，而且因为它的临床和组织学表现与其它肠道病变类似（包括乳糜泻和自体免疫性肠病），可能很难识别。本文的目的是概述文献中已经报道过的奥美沙坦相关肠道病变临床与组织学表现，同时探讨与此肠道病变不同的、其它临床病变的鉴别诊断。

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