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Improved laboratory resource utilization and patient care with the use of rapid on-site evaluation for endobronchial ultrasound fine-needle aspiration biopsy.

在纤支镜超声定位下进行细针穿刺细胞学的现场快速评价可提高实验室资源的利用和病人的治疗

Collins BT,Chen AC,Wang JF,Bernadt CT,Sanati S

Abstract

Endobronchial ultrasound guided (EBUS) fine-needle aspiration (FNA) biopsy has become widely used to evaluate patients with thoracic abnormalities. Rapid on-site evaluation (ROSE) can provide the bronchoscopist with immediate evaluation findings during the procedure. This study examines EBUS FNA biopsy procedures with and without ROSE, and investigates the impact of ROSE service on the EBUS procedure and laboratory resource utilization.
The cytopathology database at Washington University Medical Center, St. Louis, Missouri, was searched for EBUS FNA biopsy cases before and after introduction of ROSE service, and a matched cohort was collected. Reports were reviewed and pertinent data was collected, such as sites biopsied, ROSE performance, slide smears, cell blocks, and diagnostic categories. Statistical analysis of the results was performed.
A matched case-controlled EBUS FNA cohort of 340 patients (680 total) for each category of non-ROSE and ROSE service were identified. There was a 33% reduction in the number of sites biopsied with ROSE. A total of 68% of patients with ROSE had just one biopsy site compared to only 36% of non-ROSE patients. There was a 30% decrease in total slides (mean, 5.27 slides) after the introduction of ROSE. All of these improvements were statistically significant.
EBUS FNA biopsy ROSE service benefits patients by contributing to significantly fewer biopsies and improved utilization of health care resources. ROSE service results in substantially fewer total slides, which has a significant impact on the cytopathology laboratory work effort. The use of ROSE for EBUS FNA biopsy provides significant improvements in patient care and laboratory resource utilization.

摘要

纤支镜超声引导下(EBUS)的细针穿刺细胞学已经被广泛地用于评价肺部异常的病人。快速现场评价(ROSE)在术中能为纤支镜医生提供直接的评价结果。本次研究检查了伴有现场评判和无现场评判的纤支镜超声下的细针穿刺细胞学,并调查ROSE对EBUS程序和实验室资源利用的影响。
在圣路易斯华盛顿医学中心的细胞病理学数据库中搜寻在运用ROSE服务前和后的EBUSFNA活检的病例,收集匹配组的数据。回顾报告和收集相关数据,例如活检部位,ROSE的进行,玻片的涂抹,细胞块,和诊断分类。并对结果进行统计学分析。
一个匹配对照的EBUSFNA的340个病人组(总共680个病人),一个是有ROSE服务,一个没有。伴有ROSE的病人可减少33%活检部位数。总共68%的伴有ROSE的病人只需一次部位活检,相对于非-ROSE患者的36%。在引入ROSE后,总玻片数减少30%(平均5.27玻片)。所有这些改善均具有统计学意义。
EBUSFNA活检的ROSE服务有利于病人,通过导致显着意义的更少活检和改善的医疗资源的利用。ROSE服务导致大大减少的总的玻片数,对于细胞病理学实验室的工作量具有显着意义的影响。使用ROSE对于EBUSFNA的活检在病人治疗和实验室资源的利用具有显着意义的改善。

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