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Pathology Consultation on Viscoelastic Studies of Coagulopathic Obstetrical Patients.

产科凝血功能障碍患者粘弹性研究的病理会诊

Gehrie EA,Baine I,Booth GS,

Abstract

In obstetrics, the decision to transfuse blood components has historically been driven by traditional laboratory testing in combination with direct observation of bleeding. The adjunctive use of viscoelastic testing, including thromboelastometry and thromboelastography, has gained increasing acceptance in the clinical domain.
We performed a review of the published medical literature by searching the PUBMED database for keywords "viscoelastic" and "obstetric," as well as "viscoelastic" and "postpartum hemorrhage." Additionally, case reports and expert opinion publications that referenced viscoelastic studies in obstetrical patients were evaluated.
There is very little high-quality evidence currently published in the medical literature to support the notion that viscoelastic testing obviates the need for traditional coagulation testing or improves mortality resulting from major obstetrical hemorrhage.
Additional research is needed to further focus the optimum role of viscoelastic tests in major obstetrical hemorrhage.

摘要

产科确定输血历来是由传统的实验室检测结合直接观察到出血而进行的。粘弹性检测的辅助使用,包括血栓弹力测定法和血栓弹力成像术,临床领域已经接受的越来越多。我们通过在PUBMED数据库中搜索关键词“粘弹性”和“产科”以及“粘弹性”和“产后出血”,对出版的医学文献进行了综述。

此外,产科患者粘弹性研究的病例报告和出版的专家意见也进行了评估。目前医学文献中几乎没有发表过高质量证据支持这样的观点,即粘弹性检测避免了对传统凝血检测的需要或者改善了主要由产科出血引起的死亡率。尚需对成人产科出血粘弹性检测的最佳作用做进一步的研究。

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