Neurogenic polyps of the gastrointestinal tract: a clinicopathologic review with emphasis on differential diagnosis and syndromic associations.

胃肠道神经源性息肉：以鉴别诊断和综合征相关为重点的临床病理回顾

Hechtman JF,Harpaz N

阅读：446 Archives of Pathology & Laboratory Medicine； Volume 139，Issue 1 (January 2015):133-9

Abstract

Primary neurogenic gastrointestinal polyps are encountered relatively frequently in routine pathology practice. They encompass a variety of neoplastic entities with clinical, morphologic, and molecular features that reflect the diversity of neural elements within the gastrointestinal system. Although most are benign and encountered incidentally, accurate diagnosis may have important clinical implications because of the associations of certain neurogenic polyps with familial syndromes or other conditions. We review the pathology of these polyps with an emphasis on the diagnostic challenges that they pose and on newly described subtypes.

摘要

胃肠道原发性神经源性息肉在日常病理工作中常常会遇到。它们在临床、形态学和分子特点等方面具有反映胃肠道系统神经元素多样性的特点。尽管大部分为良性的、偶然发现的，准确诊断还是具有重要的临床意义，因为特定的神经源性息肉与家族综合征和其它病变相关。我们回顾了这些息肉的病理，重点在于诊断上的挑战和新近发现的一些亚型。

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