Iatrogenic Trichuris suis infection in a patient with Crohn disease.
Abstract
We report a case of biopsy-proven iatrogenic infection by the pig whipworm Trichuris suis in a patient with Crohn disease. The deliberate therapeutic ingestion of T suis ova has been adopted as an experimental approach to the treatment of Crohn disease in an effort to promote a switch from the T helper subtype 1 to T helper subtype 2 inflammatory phenotype in vivo. This report examines the morphology of the immature and adult T suis, the effects of this intervention on the immunophenotype of the bowel mucosa, and it also raises the possibility of persistent active infection in man.
我要评论
本期排行
- A 40-year-old woman with facia...
- Premature neonate with apnea a...
- A 67-year-old woman with abdom...
- Left facial mass in an elderly...
- A 63-year-old woman with chron...
- A 59-year-old woman with a spi...
- Error reduction in surgical pa...
- Improving patient safety throu...
- Neutrophil CD64 is an improved...
- Laboratory productivity and th...
共0条评论