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Three-dimensional virtual microscopy of colorectal biopsies.

Wu ML,Varga VS,Kamaras V,Ficsor L,Tagscherer A,Tulassay Z,Molnar B
阅读：301 Archives of Pathology & Laboratory Medicine； Issue 4 (April 2005)

Abstract

Conventional optical microscopy of specimens from colorectal biopsies commonly produces diagnostic errors due to incomplete sampling or poor orientation. Obtaining additional sections or re-embedding may help avoid these errors, but can prolong turnaround time. We describe new technology, which incorporates exhaustive sectioning, 3-dimensional reconstruction, and virtual microscopy, that may eliminate these problems by enabling pathologists to rapidly examine entire specimens and convert poorly oriented mucosa to well-oriented mucosa.

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