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Angiosarcoma masquerading as embryonal carcinoma in the metastasis from a mature testicular teratoma.

Sahoo S,Ryan CW,Recant WM,Yang XJ
阅读：312 Archives of Pathology & Laboratory Medicine； Issue 3 (March 2003)

Abstract

Sarcoma can arise within a germ cell tumor (GCT) from a malignant transformation of teratomatous elements or as late sequelae to radiation therapy. Angiosarcoma as a malignant component in testicular GCTs has rarely been reported and is often misdiagnosed as embryonal carcinoma. We report the case of a 23-year-old man with mature teratoma of the testis and retroperitoneal metastasis exhibiting components of mature teratoma intermingled with high-grade angiosarcoma. It is important to recognize the presence of a high-grade sarcomatous component within a GCT because of its aggressive clinical behavior and different response to therapy.

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